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Wilbourn, J. , eds (1986) Long-term and Short-term Assays for Carcinogenesis—A Critical Appraisal (IARC Scientific Publications No. , Richards, S. & Wahrendorf, J. (1980) Guidelines for simple, sensitive significance tests for carcinogenic effects in long-term animal experiments. In: IARC Monographs on the Evaluation of the Carcinogenic Risk of Chemicals to Humans, Supplement 2, Long-term and Short-term Screening Assays for Carcinogens: A Critical Appraisal, Lyon, pp. , Wilbourn, J. & Shuker, L.
A) the evidence of carcinogenicity is restricted to a single experiment; or (b) there are unresolved questions regarding the adequacy of the design, conduct or interpretation of the study; or (c) the agent or mixture increases the incidence only of benign neoplasms or lesions of uncertain neoplastic potential, or of certain neoplasms which may occur spontaneously in high incidences in certain strains. Inadequate evidence of carcinogenicity: The studies cannot be interpreted as showing either the presence or absence of a carcinogenic effect because of major qualitative or quantitative limitations.
Edited by L. K. O’Neill (1985) Vol. 8. Some Metals: As, Be, Cd, Cr, Ni, Pb, Se, Zn (IARC Scientific Publications No. 71). K. O’Neill, P. Schuller & L. Fishbein (1986) Vol. 9. Passive Smoking (IARC Scientific Publications No. 81). K. D. Brunnemann, B. Dodet & D. Hoffmann (1987) Vol. 10. Benzene and Alkylated Benzenes (IARC Scientific Publications No. 85). Edited by L. K. O’Neill (1988) Vol. 11. Polychlorinated Dioxins and Dibenzofurans (IARC Scientific Publications No. 108). Edited by C. R. Buser, B.