Central Nervous System Intraoperative Cytopathology by César R. Lacruz, Javier Saénz de Santamaría, Ricardo H.

By César R. Lacruz, Javier Saénz de Santamaría, Ricardo H. Bardales

​The necessities in Cytopathology publication sequence fulfills the necessity for an easy-to-use and authoritative synopsis of web site particular issues in cytopathology. those consultant books healthy into the lab coat pocket and are perfect for portability and quickly reference. every one quantity is seriously illustrated with a whole colour artwork software, whereas the textual content follows a ordinary define structure.

Central frightened process Intraoperative Cytopathology covers the entire spectrum of benign and malignant stipulations of the CNS with emphasis on universal issues. the quantity is seriously illustrated and comprises worthwhile algorithms that advisor the reader throughout the differential prognosis of universal and unusual entities encountered within the box of intraoperative neuro-cytopathology. Central apprehensive method Intraoperative Cytopathology is a invaluable quickly reference for pathologists, cytopathologists, and fellows and trainees facing this exigent field.​

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2). Specific Cell Groups As mentioned above, the squash technique enables us to preserve tissue structures such as papillae (Fig. 2a), whorls (Fig. 2b), rosettes, pseudorosettes (Fig. 3a), perivascular pseudorosettes (Fig. 3b), and arborizing vascular channels (Fig. 3c) on the cytologic smears. 3). Specific Cellular Elements The specific cellular elements to be considered should include Rosenthal Fibers (RFs) and EGBs in astrocytic cells; and keratin, 34 3. 2. Algorithmic Approach to CNS Intraoperative… Predominant cell types in the various tumors.

Algorithmic Approach to CNS Intraoperative… FIG. 4. Specific cellular elements. Pilocytic astrocytoma showing a clump of Rosenthal fibers (a), and an eosinophilic granular body (b) ((a, b) Smear, H&E). General Category Interpretation The rational and methodical integration of all data obtained from the evaluation of the smear serves as a basis for classifying the disease process by using the following flow chart (Fig. 8). Now some useful advice to evaluate this flowchart: Abnormal: For a case to fit this definition, it is fundamental to determine the degree of cellularity.

2009;29:641–8. Yachnis AT. Intraoperative consultation for nervous system lesions. Semin Diagn Pathol. 2002;19:192–206. Chapter 4 Normal Brain and Gliosis It is very important to become familiar with the cytologic appearance of normal brain if we want to be able to determine whether a smear is normal or not. A useful exercise is to examine smears from various regions of normal brain made from unfixed brain tissue obtained from autopsies. In this way, we will ascertain that the normal appearance varies considerably, depending on the brain region studied—cerebral cortex, basal nuclei, white matter, cerebellar cortex, choroid plexus, or leptomeninges.

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