Leptomeningeal Metastases by Neil Barshes MD, Alexis Demopoulos MD (auth.), Lauren E.

By Neil Barshes MD, Alexis Demopoulos MD (auth.), Lauren E. Abrey M.D., Marc C. Chamberlain M.D., Herbert H. Engelhard M.D., PhD. (eds.)

Leptomeningeal Metastases presents the reader with an outline of the state of the art remedy for the leptomeningeal sufferer with more information on epidemiology, symptom administration, new medical trials, and present uncomplicated learn in animal types for experimental therapies.

"Leptomeningeal metastases continues to be a devastating manifestation of hematologic malignancies and sturdy tumors. prime figures within the box assessment the pathophysiology and scientific effects of this strategy. cutting-edge remedy options are awarded highlighting advances in present management."

Steven T. Rosen, M.D.

Series Editor

Show description

Continue reading "Leptomeningeal Metastases by Neil Barshes MD, Alexis Demopoulos MD (auth.), Lauren E."

Drug Transporters by Jörg König (auth.), Martin F. Fromm, Richard B. Kim (eds.)

By Jörg König (auth.), Martin F. Fromm, Richard B. Kim (eds.)

It is more and more famous that a variety of transporter proteins are expressed in the course of the physique and ensure absorption, tissue distribution, biliary and renal removal of endogenous compounds and medication and drug results. This ebook will supply an outline at the transporter households that are most vital for drug treatment. such a lot chapters will concentrate on one transporter relatives highlighting tissue expression, substrates, inhibitors, knock-out mouse types and scientific studies.

Show description

Continue reading "Drug Transporters by Jörg König (auth.), Martin F. Fromm, Richard B. Kim (eds.)"

Diastolic Heart Failure by Gilles W. De Keulenaer MD, PhD, Dirk L. Brutsaert MD, PhD

By Gilles W. De Keulenaer MD, PhD, Dirk L. Brutsaert MD, PhD (auth.), Otto A. Smiseth MD, PhD, Michał Tendera MD, PhD (eds.)

The occurrence of center failure is expanding and but an important share of those sufferers have common left ventricular (LV) systolic functionality. In those sufferers with diastolic disorder, center failure is often often called diastolic middle failure. whereas the vast majority of examine into middle failure has focused on these sufferers with LV systolic disorder, center failure sufferers with preserved systolic functionality were grossly underinvestigated. it really is serious not just to proceed to analyze and deal with these sufferers with LV systolic disorder but additionally to enquire the probabilities in these sufferers with diastolic disorder which will supplying adapted administration of middle failure for all patients.

This e-book is the 1st to offer a entire evaluation not just of the diastolic middle failure, but in addition of alternative facets of LV diastolic functionality more often than not. It addresses the epidemiology, pathophysiologic mechanisms, diagnostic tools, therapy and diagnosis. It additionally offers an research of particular difficulties, relating to coronary artery illness, arterial high blood pressure, diabetes, hypertrophic and restrictive cardiomyopathies, and constrictive pericarditis.

The target of the Editors and their world-class panel of contributing authors has been not just to summarize the prevailing wisdom at the position of diastolic disorder in middle failure but in addition to spot the gaps within the figuring out of the matter and stimulate dialogue in those parts. for this reason, this e-book will turn out important for either easy scientists and clinicians focused on examine and medical care of sufferers with center failure. As such, cardiologists, internists and all disciplines interested by the administration of this workforce of sufferers will make the most of analyzing this book.

Show description

Continue reading "Diastolic Heart Failure by Gilles W. De Keulenaer MD, PhD, Dirk L. Brutsaert MD, PhD"

Packaging for Food Preservation by Matteo Alessandro Del Nobile, Amalia Conte (auth.)

By Matteo Alessandro Del Nobile, Amalia Conte (auth.)

The publication might be all for the 3 most crucial facets of meals packaging: Modeling, fabrics and Packaging recommendations. The modeling part will offer a whole assessment of mass delivery phenomena in polymers meant for meals packaging purposes. The fabrics part will disguise the main attention-grabbing problem-solving options within the box of nutrients packaging, i.e., low environmental impression energetic motion pictures with antimicrobial job. finally, the packaging part will offer an outline of the latest ways used to lengthen the shelf lifetime of numerous foodstuff items.

Show description

Continue reading "Packaging for Food Preservation by Matteo Alessandro Del Nobile, Amalia Conte (auth.)"

High-Tc SQUIDs for Biomedical Applications: Immunoassays, by Fredrik Öisjöen

By Fredrik Öisjöen

This thesis describes the difficult job of constructing excessive serious temperature superconducting quantum interference units (high-Tc SQUIDs) and utilizing them as sensors for biomedical purposes, together with magnetic immunoassays, magnetoencephalography and magnetic resonance imaging (MRI). the 1st a part of this paintings discusses the advance of quickly magnetic immunoassays, which are used to enhance the sensitivity, or to create new, precise point-of-care diagnostics platforms. the second one half exhibits that high-Tc SQUIDs may make magnetoencephalography extra to be had, therefore establishing the sector of high-Tc SQUID-based magnetoencephalography for recording mind services. this system will be mixed with ultra-low box MRI that is mentioned within the final half. this mix could provide a brand new certain software for experiences of mind services. This paintings doesn't easily increase on present know-how yet opens probabilities for novel complicated scientific units and techniques.

Show description

Continue reading "High-Tc SQUIDs for Biomedical Applications: Immunoassays, by Fredrik Öisjöen"

Advances in Enzymology and Related Areas of Molecular by Alton Meister

By Alton Meister

Advances in Enzymology and similar components of Molecular Biology is a seminal sequence within the box of biochemistry, providing researchers entry to authoritative stories of the most recent discoveries in all components of enzymology and molecular biology. those landmark volumes date again to 1941, delivering an unequalled view of the historic improvement of enzymology. The sequence deals researchers the newest knowing of enzymes, their mechanisms, reactions and evolution, roles in complicated organic procedure, and their software in either the laboratory and undefined. each one quantity within the sequence beneficial properties contributions via prime pioneers and investigators within the box from around the globe. All articles are conscientiously edited to make sure thoroughness, caliber, and clarity.

With its wide variety of issues and lengthy old pedigree, Advances in Enzymology and comparable parts of Molecular Biology can be utilized not just by means of scholars and researchers in molecular biology, biochemistry, and enzymology, but additionally via any scientist attracted to the invention of an enzyme, its houses, and its purposes.

Content:

Show description

Continue reading "Advances in Enzymology and Related Areas of Molecular by Alton Meister"

ACL Injuries in the Female Athlete: Causes, Impacts, and by Frank R. Noyes M.D., Sue D. Barber-Westin B.S. (auth.),

By Frank R. Noyes M.D., Sue D. Barber-Westin B.S. (auth.), Frank R. Noyes, Sue Barber-Westin (eds.)

Nearly one million anterior cruciate ligament (ACL) accidents take place every year world wide, inflicting long term difficulties within the knee joint. This textbook examines the fast- and long term affects of ACL accidents at the foundation of hundreds of thousands of released stories. chance elements for such accidents are explored utilizing facts from hypothesis-driven investigations, and attainable factors of the better chance of noncontact ACL accidents in woman athletes are analyzed. Neuromuscular education courses proven to minimize the speed of those accidents in lady athletes are defined in step by step element via a variety of colour pictures and video demonstrations. furthermore, precise descriptions are supplied for rehabilitation courses for use after ACL reconstruction with the intention to decrease the danger of a destiny damage. The e-book might be of worth to orthopedic surgeons, actual therapists, athletic running shoes, activities medication basic care physicians, and energy and conditioning specialists.

Show description

Continue reading "ACL Injuries in the Female Athlete: Causes, Impacts, and by Frank R. Noyes M.D., Sue D. Barber-Westin B.S. (auth.),"

Power Supply Devices and Systems of Relay Protection by Vladimir Gurevich

By Vladimir Gurevich

Energy offer units and platforms of Relay safety brings relay safeguard and electrical energy engineers a unmarried, centred resource of knowledge on auxiliary energy offer structures and units. The ebook additionally tackles particular difficulties and options of relay defense strength offer platforms and units, that are usually now not handled within the literature. the writer, an skilled engineer with greater than 100 Read more...

Show description

Continue reading "Power Supply Devices and Systems of Relay Protection by Vladimir Gurevich"

Biomarkers in Breast Cancer: Molecular Diagnostics for by Richard M. Simon DSc (auth.), Giampietro Gasparini MD,

By Richard M. Simon DSc (auth.), Giampietro Gasparini MD, Daniel F. Hayes MD (eds.)

It is now good well-known that individualized melanoma remedy making plans, according to tumor features particular to an individual's melanoma, makes it more straightforward to pick these probably to profit from poisonous melanoma cures and to prevent treating these least prone to profit. In Biomarkers in Breast melanoma: Molecular Diagnostics for Predicting and tracking healing influence, professional laboratory and scientific researchers from around the globe evaluate how one can layout and review reviews of tumor markers, in addition to research their use in breast melanoma sufferers. The authors hide either the key advances in subtle molecular tools and the state of the art in traditional prognostic and predictive symptoms. one of the subject matters mentioned are the relevance of rigorous examine layout and instructions to the validation of latest biomarkers, gene expression profiling by means of tissue microarrays, adjuvant systemic treatment, and using estrogen, progesterone, and epidermal development issue receptors as either prognostic and predictive symptoms. Highlights comprise the overview of HER2 and EGFR kinfolk, of p53, and of UPA/PAI-1; the detection of infrequent cells in blood and marrow; and the detection and research of soluble, circulating markers.
Authoritative and state of the art, Biomarkers in Breast melanoma: Molecular Diagnostics for Predicting and tracking healing impact bargains laboratory investigators constructing new tumor markers, scientific investigators checking out them, and clinicians utilizing them an up to date knowing of either the prognostic/predictive signs and the radical molecular-targeted cures appropriate for individualizing breast melanoma therapy.

Show description

Continue reading "Biomarkers in Breast Cancer: Molecular Diagnostics for by Richard M. Simon DSc (auth.), Giampietro Gasparini MD,"

Organophosphorus Chemistry Volume 41 by David W Allen, David Loakes, John C Tebby, Helen

By David W Allen, David Loakes, John C Tebby, Helen Groombridge, Gyorgy Keglevich, Irina Odinets, M Migaud, Piotr Balczewski, Gerd-Volker Roeschenthaler, Frederick Stewart, Robert Slinn, Joanna Skalik

Content material: Phosphines and comparable P-C bonded Compounds; Tervalent Phosphorus Acid Derivatives; Phosphine Chalcogenides;Phosphonium Salts and P-Ylides; Nucleotides and Nucleic Acids: Mononucleotides; Nucleotides and Nucleic Acids: Oligo- and Poly-Nucleotides Quinquevalent Phosphorus Acids; Pentacoordinated and Hexacoordinated Compounds; Phosphazenes; actual tools in Organophosphorus Chemistry

Show description

Continue reading "Organophosphorus Chemistry Volume 41 by David W Allen, David Loakes, John C Tebby, Helen"